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    Projects

    Present Projects:

    1. For wide utilisation potential (Red, White and Green Biotechnology)of algae furthermore for their inhibition in technologycal facilities we started a new research in cooperation with (Paks Nuclear Power Plant Ltd) in 2012.
    2. Our ongoing researches are enclosed in the R+D+I strategy of BUTE supported by a government project entitled "Development of quality-oriented and harmonized R+D+I strategy and functional model at BME" with project ID: TAMOP-4.2.1/B-09/1/KMR-2010-0002
    3. Our reserach group is taking part in an electronic lecture notes development project supported by the Hungarian Government (TAMOP-4.1.2-08/2/A/KMR-2009-0028) entitled "Development of multidisciplinar digital lecture notes in modul system for the chemical engineer and bioengineer education". Our research grop is developing the Bioengineering Processes, Bioseparation processes, and Industrial Microbiology lecture notes.
    4. Development of integrated agricultural cultivation, storaging, processing, and logistical system of sweet sorghum (Government grant). The work of our researchgroup will be the examination of the fermentative possibilities of sweetsorghum pressed juice into high value added chemicals (White biotechnology)
    5. Utilization of biofuel by-products (in association with Nitrokémia 2000 Inc., Cereol Inc. and Bábolna Bioenvironmental Centre Inc.)
      1. Fermentative production of dihydroxy-aceton and L-erythrulose by Gluconobacter oxydans
        • macrokinetic description of oxidative Gluconobacter fermentations for optimization purposes
        • media development in order to enhance downstream processes
      2. Biological transformation of 1,3-propanediol
        • optimization of enzyme production by native and recombinant strains for the coenzyme coupled enzymatic production of 1,3-propanediol
        • downstream optimization of the enzymes
        • kinetic modeling of enzyme systems for reactor design purposes
    6. Development of Starch based Bioethanol and Biogas producing Technology (in association with Frings-Austria Ltd. (Austria))
    7. Pilot production of a viral preparation against Fire blight (Erwinia amylovora) of apples and pears (Enviroinvest-Waste Ltd.)
    8. Development of Starch based Lactic acid and poli-lactic acid (PLA) producing Technology
      (in association with Cosimex Ltd. (Hungary), ChemCon Ltd. (Hungary) Nordbiochem LLC (Estonia), and a href="http://nitrokemia.hu" target="_blank">Nitrokémia - Hunest (Hungary))
    9. Production of recombinant thromboplastin (in association with Diagon Ltd. (Hungary))

    Past projects:

    1. Recombinant Pichia pastoris project – 1st cycle
      The project covers:
      • statistical and kinetic model based optimization of pH, temperature and methanol concentration, with special attention on GS115 MutS and SMD1168 strains
      • characterization of Figaro TGS822 based on-line methanol concentration measurement and control system
      • statistical and kinetic model based analysis of dissolved oxygen control of substrate inlet
      • kinetic modeling of GS115 MutS strains
      • development of novel recombinant strains (e.g. for human serum albumin, 1,3-propandediol-oxydoreductase production)
      • development of quantitative screening method for successful strain selection
      • downstream optimization of recombinant products
    2. Development of fermentative itaconic acid production (in association with Nitrokémia 2000 Inc.)
      • statistical optimization of sporulation media of Aspergillus terreus
      • production optimization of itaconic acid production
      • scale-up to pilot scale reactor
    3. Utilization of lactic by-products for producing heavy-metal absorbing yeasts (in association with Vireco Ltd.)
      • statistically based screening and media development of lactic strains in odder to gain high cell yields on whey
      • development and test of pilot scale fermentation procedure
      • development of cell mass drying procedures
      • statistical analysis of the heavy-metal absorbing capacity of the produced cell mass and development of recycling techniques